General Structure Information
| PDB ID | 1v5w |
| HGNC Gene Label(s) | DMC1 |
| Structure Name | crystal structure of the human dmc1 protein |
| Resolution | 3.2Å |
| Reference | AUTH T.KINEBUCHI,W.KAGAWA,R.ENOMOTO,K.TANAKA,K.MIYAGAWA,AUTH 2 T.SHIBATA,H.KURUMIZAKA,S.YOKOYAMATITL STRUCTURAL BASIS FOR OCTAMERIC RING FORMATION AND DNATITL 2 INTERACTION OF THE HUMAN HOMOLOGOUS-PAIRING PROTEIN DMC1REF MOL.CELL V. 14 363 2004REFN ISSN 1097-2765PMID 15125839DOI 10.1016/S1097-2765(04)00218-7 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 239 |
| Number Of SNVs | 53 |
| Number Of Permutations | 9031 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.022 |
| p-value | 0.734 |
COSMIC
| Number Of Residues | 239 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1140 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.067 |
| p-value | 0.174 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 53 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.162 |
| p-value | 0.578 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
