General Structure Information
| PDB ID | 2p2r |
| HGNC Gene Label(s) | PCBP2 |
| Structure Name | crystal structure of the third kh domain of human poly(c)- binding protein-2 in complex with c-rich strand of human telomeric dna |
| Resolution | 1.6Å |
| Reference | AUTH S.FENN,Z.DU,J.K.LEE,R.TJHEN,R.M.STROUD,T.L.JAMESTITL CRYSTAL STRUCTURE OF THE THIRD KH DOMAIN OF HUMANTITL 2 POLY(C)-BINDING PROTEIN-2 IN COMPLEX WITH A C-RICHTITL 3 STRAND OF HUMAN TELOMERIC DNA AT 1.6 A RESOLUTION.REF NUCLEIC ACIDS RES. V. 35 2651 2007REFN ISSN 0305-1048PMID 17426136DOI 10.1093/NAR/GKM139 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 72 |
| Number Of SNVs | 6 |
| Number Of Permutations | 806 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.133 |
| p-value | 0.569 |
COSMIC
| Number Of Residues | 72 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.333 |
| p-value | 0.539 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 6 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.4 |
| p-value | 0.426 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
