General Structure Information
| PDB ID | 2z7q |
| HGNC Gene Label(s) | RPS6KA1 |
| Structure Name | crystal structure of the n-terminal kinase domain of human rsk-1 bound to amp-pcp |
| Resolution | 2.0Å |
| Reference | AUTH M.IKUTA,M.KORNIENKO,N.BYRNE,J.C.REID,S.MIZUARAI,H.KOTANI,AUTH 2 S.K.MUNSHITITL CRYSTAL STRUCTURES OF THE N-TERMINAL KINASE DOMAIN OF HUMANTITL 2 RSK1 BOUND TO THREE DIFFERENT LIGANDS: IMPLICATIONS FOR THETITL 3 DESIGN OF RSK1 SPECIFIC INHIBITORS.REF PROTEIN SCI. V. 16 2626 2007REFN ISSN 0961-8368PMID 17965187DOI 10.1110/PS.073123707 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 255 |
| Number Of SNVs | 37 |
| Number Of Permutations | 19138 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.063 |
| p-value | 0.044 |