General Structure Information
| PDB ID | 2dyb |
| HGNC Gene Label(s) | NCF4 |
| Structure Name | the crystal structure of human p40(phox) |
| Resolution | 3.15Å |
| Reference | AUTH K.HONBOU,R.MINAKAMI,S.YUZAWA,R.TAKEYA,N.N.SUZUKI,AUTH 2 S.KAMAKURA,H.SUMIMOTO,F.INAGAKITITL FULL-LENGTH P40PHOX STRUCTURE SUGGESTS A BASIS FORTITL 2 REGULATION MECHANISM OF ITS MEMBRANE BINDING.REF EMBO J. V. 26 1176 2007REFN ISSN 0261-4189PMID 17290225DOI 10.1038/SJ.EMBOJ.7601561 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 272 |
| Number Of SNVs | 83 |
| Number Of Permutations | 21626 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.232 |
| p-value | 0.103 |
COSMIC
| Number Of Residues | 272 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1942 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.2 |
| p-value | 0.26 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 83 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.134 |
| p-value | 0.395 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
