General Structure Information
| PDB ID | 1ug3 |
| HGNC Gene Label(s) | EIF4G1 |
| Structure Name | c-terminal portion of human eif4gi |
| Resolution | 2.24Å |
| Reference | AUTH L.BELLSOLELL,P.F.CHO-PARK,F.POULIN,N.SONENBERG,AUTH 2 S.K.BURLEYTITL TWO STRUCTURALLY ATYPICAL HEAT DOMAINS IN THETITL 2 C-TERMINAL PORTION OF HUMAN EIF4G SUPPORT BINDINGTITL 3 TO EIF4A AND MNK1REF STRUCTURE V. 14 913 2006REFN ISSN 0969-2126PMID 16698542DOI 10.1016/J.STR.2006.03.012 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 323 |
| Number Of SNVs | 76 |
| Number Of Permutations | 21554 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.019 |
| p-value | 0.579 |
COSMIC
| Number Of Residues | 323 |
| Number Of SNVs | 4 |
| Number Of Permutations | 257 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.5 |
| p-value | 0.315 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.382 |
| p-value | 0.188 |