General Structure Information
| PDB ID | 1waw |
| HGNC Gene Label(s) | CHIT1 |
| Structure Name | specificity and affinity of natural product cyclopentapeptide inhibitor argadin against human chitinase |
| Resolution | 1.75Å |
| Reference | AUTH F.V.RAO,D.R.HOUSTON,R.G.BOOT,J.M.F.G.AERTS,M.HODKINSON,AUTH 2 D.J.ADAMS,K.SHIOMI,S.OMURA,D.M.F.VAN AALTENTITL SPECIFICITY AND AFFINITY OF NATURAL PRODUCTTITL 2 CYCLOPENTAPEPTIDE INHIBITORS AGAINST ASPERGILLUS FUMIGATUS,TITL 3 HUMAN AND BACTERIAL CHITINASESREF CHEM.BIOL. V. 12 65 2005REFN ISSN 1074-5521PMID 15664516DOI 10.1016/J.CHEMBIOL.2004.10.013 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 366 |
| Number Of SNVs | 117 |
| Number Of Permutations | 48504 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.024 |
| p-value | 0.697 |
COSMIC
| Number Of Residues | 366 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1871 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.048 |
| p-value | 0.676 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 117 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.083 |
| p-value | 0.58 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
