General Structure Information
| PDB ID | 3io2 |
| HGNC Gene Label(s) | EP300 |
| Structure Name | crystal structure of the taz2 domain of p300 |
| Resolution | 2.5Å |
| Reference | AUTH M.MILLER,Z.DAUTER,S.CHERRY,J.E.TROPEA,A.WLODAWERTITL STRUCTURE OF THE TAZ2 DOMAIN OF P300: INSIGHTS INTO LIGANDTITL 2 BINDING.REF ACTA CRYSTALLOGR.,SECT.D V. 65 1301 2009REFN ISSN 0907-4449PMID 19966416DOI 10.1107/S0907444909040153 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 109 |
| Number Of SNVs | 6 |
| Number Of Permutations | 1369 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.2 |
| p-value | 0.217 |
COSMIC
| Number Of Residues | 109 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.333 |
| p-value | 0.945 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 6 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | -0.333 |
| p-value | 0.834 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
