General Structure Information
| PDB ID | 1k78 |
| HGNC Gene Label(s) | PAX5 |
| Structure Name | pax5(1-149)+ets-1(331-440)+dna |
| Resolution | 2.25Å |
| Reference | AUTH C.W.GARVIE,J.HAGMAN,C.WOLBERGERTITL STRUCTURAL STUDIES OF ETS-1/PAX5 COMPLEX FORMATIONTITL 2 ON DNA.REF MOL.CELL V. 8 1267 2001REFN ISSN 1097-2765PMID 11779502DOI 10.1016/S1097-2765(01)00410-5 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 124 |
| Number Of SNVs | 8 |
| Number Of Permutations | 1802 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.143 |
| p-value | 0.143 |
COSMIC
| Number Of Residues | 124 |
| Number Of SNVs | 5 |
| Number Of Permutations | 130 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.4 |
| p-value | 0.12 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

