General Structure Information
| PDB ID | 2jed |
| HGNC Gene Label(s) | PRKCQ |
| Structure Name | the crystal structure of the kinase domain of the protein kinase c theta in complex with nvp-xaa228 at 2.32a resolution. |
| Resolution | 2.32Å |
| Reference | AUTH W.STARK,F.BITSCH,A.BERNER,F.BUELENS,P.GRAFF,AUTH 2 H.DEPERSIN,G.FENDRICH,M.GEISER,R.KNECHT,J.RAHUEL,AUTH 3 G.RUMMEL,J.M.SCHLAEPPI,R.SCHMITZ,A.STRAUSS,J.WAGNERTITL THE CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF THETITL 2 PROTEIN KINASE C THETA IN COMPLEX WITH NVP-XAA228REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 315 |
| Number Of SNVs | 56 |
| Number Of Permutations | 9925 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.256 |
| p-value | 0.272 |
COSMIC
| Number Of Residues | 315 |
| Number Of SNVs | 8 |
| Number Of Permutations | 2696 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.036 |
| p-value | 0.788 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 56 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.158 |
| p-value | 0.567 |