2QPW.A | PRDM2

PDB ID	2qpw
HGNC Gene Label(s)	PRDM2
Structure Name	methyltransferase domain of human pr domain-containing protein 2
Resolution	1.79Å
Reference	AUTH H.WU,J.MIN,V.V.LUNIN,T.ANTOSHENKO,L.DOMBROVSKI,AUTH 2 H.ZENG,A.ALLALI-HASSANI,V.CAMPAGNA-SLATER,M.VEDADI,AUTH 3 C.H.ARROWSMITH,A.N.PLOTNIKOV,M.SCHAPIRATITL STRUCTURAL BIOLOGY OF HUMAN H3K9 METHYLTRANSFERASESREF PLOS ONE V. 5 E8570 2010REFN ESSN 1932-6203PMID 20084102DOI 10.1371/JOURNAL.PONE.0008570

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
1:14057498		T>A	A:4	(9.27, 23.96, -7.98)
1:14057514	rs369625913	A>V	A:9	(11.96, 13.40, -15.10)
1:14057519		T>A	A:11	(7.27, 9.39, -11.54)
1:14057522		E>K	A:12	(8.26, 5.36, -8.00)
1:14057532	COSM3472815 COSM3472816	A>V	A:15	(2.00, 0.40, -10.51)
1:14057553		L>R	A:22	(2.94, -5.33, -2.81)
1:14057556	rs370173337	R>Q	A:23	(2.88, -11.15, -2.88)
1:14057578	rs184864123	R>S	A:30	(-0.30, 0.95, 3.81)
1:14057594		V>I	A:36	(9.92, 13.50, 1.92)
1:14057598		D>G	A:37	(9.97, 12.53, -2.95)
1:14059285		T>A	A:46	(-1.27, 0.72, 9.42)
1:14059288		K>Q	A:47	(-1.02, -0.93, 13.60)
1:14059291		P>S	A:48	(0.09, 1.20, 16.56)
1:14059309		K>E	A:54	(13.37, -6.70, 13.88)
1:14059324		V>I	A:59	(17.68, -7.84, 0.25)
1:14059334		K>R	A:62	(26.72, -9.47, -2.95)
1:14059339		K>E	A:64	(33.02, -4.06, -6.74)
1:14059369	rs113167703	M>L	A:74	(23.51, 1.24, -0.52)
1:14068539		T>P	A:90	(18.60, 0.36, -7.44)
1:14068540	rs146971236	T>S	A:90	(18.60, 0.36, -7.44)
1:14068576		N>S	A:102	(12.81, 7.83, 2.26)
1:14068591		G>E	A:107	(17.38, 13.11, 10.82)
1:14068632		I>V	A:121	(21.00, -4.40, 7.25)
1:14075863		A>V	A:130	(1.74, 6.57, 14.42)
1:14075887		W>S	A:138	(20.46, 9.67, 9.26)
1:14075901	rs551419635	D>N	A:143	(23.85, 9.25, 22.45)
1:14075914		I>R	A:147	(26.23, 15.49, 32.04)

2QPW.A | PRDM2.