General Structure Information
| PDB ID | 4ic7 |
| HGNC Gene Label(s) | MAP2K5 |
| Structure Name | crystal structure of the erk5 kinase domain in complex with an mkk5 binding fragment |
| Resolution | 2.6Å |
| Reference | AUTH G.GLATZ,G.GOGL,A.ALEXA,A.REMENYITITL STRUCTURAL MECHANISM FOR THE SPECIFIC ASSEMBLY ANDTITL 2 ACTIVATION OF THE EXTRACELLULAR SIGNAL REGULATED KINASE 5TITL 3 (ERK5) MODULE.REF J.BIOL.CHEM. V. 288 8596 2013REFN ISSN 0021-9258PMID 23382384DOI 10.1074/JBC.M113.452235 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 115 |
| Number Of SNVs | 29 |
| Number Of Permutations | 10995 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.468 |
| p-value | 0.126 |