2KIE.A | OCRL – ASTRID

2KIE.A | OCRL

PDB ID	2kie
HGNC Gene Label(s)	OCRL
Structure Name	a ph domain within ocrl bridges clathrin mediated membrane trafficking to phosphoinositide metabolis
Resolution	-1.0Å
Reference	AUTH Y.MAO,D.M.BALKIN,R.ZONCU,K.S.ERDMANN,L.TOMASINI,AUTH 2 F.HU,M.M.JIN,M.E.HODSDON,P.DE CAMILLITITL A PH DOMAIN WITHIN OCRL BRIDGES CLATHRIN-MEDIATEDTITL 2 MEMBRANE TRAFFICKING TO PHOSPHOINOSITIDE METABOLISMREF EMBO J. V. 28 1831 2009REFN ISSN 0261-4189PMID 19536138DOI 10.1038/EMBOJ.2009.155

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
X:128674433		P>L	A:11	(-2.69, 8.19, 10.35)
X:128674721	rs371099243	T>A	A:19	(-5.95, -3.55, 6.64)
X:128674722	rs61752970	T>I	A:19	(-5.95, -3.55, 6.64)
X:128674731	COSM3913338	G>A	A:22	(2.83, -7.78, 3.37)
X:128674733		M>V	A:23	(6.20, -9.94, 2.86)
X:128674748		P>S	A:28	(19.75, -4.41, -0.88)
X:128674755	rs368472232	R>P	A:30	(12.16, -10.00, 2.58)
X:128674767		A>V	A:34	(1.90, -3.80, 6.01)
X:128674772		T>S	A:36	(-3.15, 0.29, 5.16)
X:128674773		T>I	A:36	(-3.15, 0.29, 5.16)
X:128674778		A>S	A:38	(-6.49, 5.29, 4.09)
X:128674782		Q>R	A:39	(-10.93, 8.45, 2.61)
X:128674796		Y>H	A:44	(-9.13, 7.93, -2.16)
X:128678967		H>R	A:56	(5.53, -0.85, 13.37)
X:128678987		I>V	A:63	(-3.55, 7.31, -3.78)
X:128678990		N>D	A:64	(-1.23, 11.31, -6.71)
X:128678995		S>R	A:65	(0.02, 11.46, -10.85)
X:128679012		Q>R	A:71	(0.29, -6.09, -10.13)
X:128682545		E>K	A:74	(6.37, -1.73, -17.50)
X:128682575	rs146556695	N>D	A:84	(-5.22, -12.15, -8.04)
X:128691307		C>R	A:87	(-0.00, -9.84, -5.62)
X:128691328		D>H	A:94	(8.16, 12.57, -5.43)
X:128691346	COSM124904	R>C	A:100	(10.37, -5.46, -5.98)
X:128691347		R>H	A:100	(10.37, -5.46, -5.98)