General Structure Information
| PDB ID | 3qt2 |
| HGNC Gene Label(s) | IL5RA |
| Structure Name | structure of a cytokine ligand-receptor complex |
| Resolution | 2.55Å |
| Reference | AUTH E.PATINO,A.KOTZSCH,S.SAREMBA,J.NICKEL,W.SCHMITZ,W.SEBALD,AUTH 2 T.D.MUELLERTITL STRUCTURE ANALYSIS OF THE IL-5 LIGAND-RECEPTOR COMPLEXTITL 2 REVEALS A WRENCH-LIKE ARCHITECTURE FOR IL-5RALPHA.REF STRUCTURE V. 19 1864 2011REFN ISSN 0969-2126PMID 22153509DOI 10.1016/J.STR.2011.08.015 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 307 |
| Number Of SNVs | 97 |
| Number Of Permutations | 28736 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.019 |
| p-value | 0.887 |
COSMIC
| Number Of Residues | 307 |
| Number Of SNVs | 9 |
| Number Of Permutations | 4504 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.083 |
| p-value | 0.967 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 97 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.08 |
| p-value | 0.463 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
