General Structure Information
| PDB ID | 3gut |
| HGNC Gene Label(s) | RELA |
| Structure Name | crystal structure of a higher-order complex of p50:rela bound to the hiv-1 ltr |
| Resolution | 3.59Å |
| Reference | AUTH J.C.STROUD,A.OLTMAN,A.HAN,D.L.BATES,L.CHENTITL STRUCTURAL BASIS OF HIV-1 ACTIVATION BYTITL 2 NF-KAPPAB–A HIGHER-ORDER COMPLEX OF P50:RELA BOUNDTITL 3 TO THE HIV-1 LTR.REF J.MOL.BIOL. V. 393 98 2009REFN ISSN 0022-2836PMID 19683540DOI 10.1016/J.JMB.2009.08.023 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 272 |
| Number Of SNVs | 36 |
| Number Of Permutations | 26260 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.4 |
| p-value | 0.221 |
COSMIC
| Number Of Residues | 272 |
| Number Of SNVs | 5 |
| Number Of Permutations | 2843 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.2 |
| p-value | 0.163 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 36 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | -0.225 |
| p-value | 0.292 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
