General Structure Information
| PDB ID | 3f8u |
| HGNC Gene Label(s) | TAPBP |
| Structure Name | tapasin/erp57 heterodimer |
| Resolution | 2.6Å |
| Reference | AUTH G.DONG,P.A.WEARSCH,D.R.PEAPER,P.CRESSWELL,K.M.REINISCHTITL INSIGHTS INTO MHC CLASS I PEPTIDE LOADING FROM THE STRUCTURETITL 2 OF THE TAPASIN-ERP57 THIOL OXIDOREDUCTASE HETERODIMER.REF IMMUNITY V. 30 21 2009REFN ISSN 1074-7613PMID 19119025DOI 10.1016/J.IMMUNI.2008.10.018 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 361 |
| Number Of SNVs | 95 |
| Number Of Permutations | 67356 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.273 |
| p-value | 0.035 |
COSMIC
| Number Of Residues | 361 |
| Number Of SNVs | 3 |
| Number Of Permutations | 255 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.667 |
| p-value | 0.303 |
Ripley’s K Analysis Plots
COSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
