General Structure Information
| PDB ID | 2ge9 |
| HGNC Gene Label(s) | BTK |
| Structure Name | solution structures of the sh2 domain of brutons tyrosine kinase |
| Resolution | -1.0Å |
| Reference | AUTH K.-C.HUANG,H.-T.CHENG,M.-T.PAI,S.-R.TZENG,AUTH 2 J.-W.CHENGTITL SOLUTION STRUCTURE AND PHOSPHOPEPTIDE BINDING OFTITL 2 THE SH2 DOMAIN FROM THE HUMAN BRUTONS TYROSINETITL 3 KINASEREF J.BIOMOL.NMR V. 36 73 2006REFN ISSN 0925-2738PMID 16969585DOI 10.1007/S10858-006-9064-3 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 118 |
| Number Of SNVs | 4 |
| Number Of Permutations | 243 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.0 |
| p-value | 0.281 |
ClinVar
| Number Of Residues | 118 |
| Number Of SNVs | 5 |
| Number Of Permutations | 356 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.4 |
| p-value | 0.042 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 4 |
| Number Of ClinVar SNVs | 5 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.4 |
| p-value | 0.141 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
