2ODD.A | RUNX1T1

General Structure Information

PDB ID 2odd
HGNC Gene Label(s) RUNX1T1
Structure Name solution structure of the mynd domain from aml1-eto complexed with smrt, a corepressor
Resolution -1.0Å
Reference AUTH Y.LIU,W.CHEN,J.GAUDET,M.D.CHENEY,L.ROUDAIA,AUTH 2 T.CIERPICKI,R.C.KLET,K.HARTMAN,T.M.LAUE,N.A.SPECK,AUTH 3 J.H.BUSHWELLERTITL STRUCTURAL BASIS FOR RECOGNITION OF SMRT/N-COR BYTITL 2 THE MYND DOMAIN AND ITS CONTRIBUTION TO AML1/ETOSTITL 3 ACTIVITY.REF CANCER CELL V. 11 483 2007REFN ISSN 1535-6108PMID 17560331DOI 10.1016/J.CCR.2007.04.010

Variant Set Distributions

ExAC Variants

Number Of Residues 50
Number Of SNVs 4
Number Of Permutations 593
Optimal Distance Threshold 8.0
K Statistic 0.333
p-value 0.616
COSMIC

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants