General Structure Information
| PDB ID | 4ag4 |
| HGNC Gene Label(s) | DDR1 |
| Structure Name | crystal structure of a ddr1-fab complex |
| Resolution | 2.8Å |
| Reference | AUTH F.CARAFOLI,M.C.MAYER,K.SHIRAISHI,M.A.PECHEVA,L.Y.CHAN,R.NAN,AUTH 2 B.LEITINGER,E.HOHENESTERTITL STRUCTURE OF THE DISCOIDIN DOMAIN RECEPTOR 1 EXTRACELLULARTITL 2 REGION BOUND TO AN INHIBITORY FAB FRAGMENT REVEALS FEATURESTITL 3 IMPORTANT FOR SIGNALING.REF STRUCTURE V. 20 688 2012REFN ISSN 0969-2126PMID 22483115DOI 10.1016/J.STR.2012.02.011 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 338 |
| Number Of SNVs | 85 |
| Number Of Permutations | 11670 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.159 |
| p-value | 0.211 |
COSMIC
| Number Of Residues | 338 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 85 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.462 |
| p-value | 0.182 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
