General Structure Information
| PDB ID | 2kyg |
| HGNC Gene Label(s) | RUNX1T1 |
| Structure Name | structure of the aml1-eto nervy domain – pka(riia) complex and its contribution to aml1-eto activity |
| Resolution | -1.0Å |
| Reference | AUTH T.CORPORA,L.ROUDAIA,Z.M.OO,W.CHEN,E.MANUYLOVA,X.CAI,AUTH 2 M.J.CHEN,T.CIERPICKI,N.A.SPECK,J.H.BUSHWELLERTITL STRUCTURE OF THE AML1-ETO NHR3-PKA(RIIALPHA) COMPLEX AND ITSTITL 2 CONTRIBUTION TO AML1-ETO ACTIVITY.REF J.MOL.BIOL. V. 402 560 2010REFN ISSN 0022-2836PMID 20708017DOI 10.1016/J.JMB.2010.08.007 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 31 |
| Number Of SNVs | 7 |
| Number Of Permutations | 524 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.286 |
| p-value | 0.566 |
COSMIC
| Number Of Residues | 31 |
| Number Of SNVs | 3 |
| Number Of Permutations | 16 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.667 |
| p-value | 0.343 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
