General Structure Information
| PDB ID | 3kuc |
| HGNC Gene Label(s) | RAP1A |
| Structure Name | complex of rap1a(e30d/k31e)gdp with rafrbd(a85k/n71r) |
| Resolution | 1.92Å |
| Reference | AUTH D.FILCHTINSKI,O.SHARABI,A.RUPPEL,I.R.VETTER,C.HERRMANN,AUTH 2 J.M.SHIFMANTITL WHAT MAKES RAS AN EFFICIENT MOLECULAR SWITCH: ATITL 2 COMPUTATIONAL, BIOPHYSICAL, AND STRUCTURAL STUDY OF RAS-GDPTITL 3 INTERACTIONS WITH MUTANTS OF RAF.REF J.MOL.BIOL. V. 399 422 2010REFN ISSN 0022-2836PMID 20361980DOI 10.1016/J.JMB.2010.03.046 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 167 |
| Number Of SNVs | 18 |
| Number Of Permutations | 4652 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.039 |
| p-value | 0.801 |
COSMIC
| Number Of Residues | 167 |
| Number Of SNVs | 3 |
| Number Of Permutations | 77 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.667 |
| p-value | 0.576 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 18 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.373 |
| p-value | 0.834 |