General Structure Information
| PDB ID | 3mmy |
| HGNC Gene Label(s) | RAE1 |
| Structure Name | structural and functional analysis of the interaction between the nucleoporin nup98 and the mrna export factor rae1 |
| Resolution | 1.65Å |
| Reference | AUTH Y.REN,H.S.SEO,G.BLOBEL,A.HOELZTITL STRUCTURAL AND FUNCTIONAL ANALYSIS OF THE INTERACTIONTITL 2 BETWEEN THE NUCLEOPORIN NUP98 AND THE MRNA EXPORT FACTORTITL 3 RAE1.REF PROC.NATL.ACAD.SCI.USA V. 107 10406 2010REFN ISSN 0027-8424PMID 20498086DOI 10.1073/PNAS.1005389107 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 354 |
| Number Of SNVs | 45 |
| Number Of Permutations | 26016 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.118 |
| p-value | 0.093 |
COSMIC
| Number Of Residues | 354 |
| Number Of SNVs | 5 |
| Number Of Permutations | 423 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.1 |
| p-value | 0.683 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 45 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.136 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
