3SF4.B | GPSM2

General Structure Information

PDB ID 3sf4
HGNC Gene Label(s) GPSM2
Structure Name crystal structure of the complex between the conserved cell polarity proteins inscuteable and lgn
Resolution 2.6Å
Reference AUTH S.YUZAWA,S.KAMAKURA,Y.IWAKIRI,J.HAYASE,H.SUMIMOTOTITL STRUCTURAL BASIS FOR INTERACTION BETWEEN THE CONSERVED CELLTITL 2 POLARITY PROTEINS INSCUTEABLE AND LEU-GLY-ASNTITL 3 REPEAT-ENRICHED PROTEIN (LGN)REF PROC.NATL.ACAD.SCI.USA V. 108 19210 2011REFN ISSN 0027-8424PMID 22074847DOI 10.1073/PNAS.1110951108

Variant Set Distributions

ExAC Variants

Number Of Residues 350
Number Of SNVs 74
Number Of Permutations 57540
Optimal Distance Threshold 30.0
K Statistic 0.414
p-value 0.306
COSMIC

Number Of Residues 350
Number Of SNVs 3
Number Of Permutations 7
Optimal Distance Threshold 30.0
K Statistic 0.333
p-value 1.0

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants