General Structure Information
| PDB ID | 3sf4 |
| HGNC Gene Label(s) | GPSM2 |
| Structure Name | crystal structure of the complex between the conserved cell polarity proteins inscuteable and lgn |
| Resolution | 2.6Å |
| Reference | AUTH S.YUZAWA,S.KAMAKURA,Y.IWAKIRI,J.HAYASE,H.SUMIMOTOTITL STRUCTURAL BASIS FOR INTERACTION BETWEEN THE CONSERVED CELLTITL 2 POLARITY PROTEINS INSCUTEABLE AND LEU-GLY-ASNTITL 3 REPEAT-ENRICHED PROTEIN (LGN)REF PROC.NATL.ACAD.SCI.USA V. 108 19210 2011REFN ISSN 0027-8424PMID 22074847DOI 10.1073/PNAS.1110951108 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 350 |
| Number Of SNVs | 74 |
| Number Of Permutations | 57540 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.414 |
| p-value | 0.306 |
COSMIC
| Number Of Residues | 350 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

