General Structure Information
| PDB ID | 1o7b |
| HGNC Gene Label(s) | TNFAIP6 |
| Structure Name | refined solution structure of the human tsg-6 link module |
| Resolution | -1.0Å |
| Reference | AUTH C.D.BLUNDELL,D.MAHONEY,A.ALMOND,P.DEANGELIS,AUTH 2 J.D.KAHMANN,P.TERIETE,A.R.PICKFORD,I.D.CAMPBELL,AUTH 3 A.J.DAYTITL THE LINK MODULE FROM OVULATION- ANDTITL 2 INFLAMMATION-ASSOCIATED PROTEIN TSG-6 CHANGESTITL 3 CONFORMATION ON HYALURONAN BINDINGREF J.BIOL.CHEM. V. 278 49261 2003REFN ISSN 0021-9258PMID 12972412DOI 10.1074/JBC.M309623200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 98 |
| Number Of SNVs | 24 |
| Number Of Permutations | 4898 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.138 |
| p-value | 0.652 |
COSMIC
| Number Of Residues | 98 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.333 |
| p-value | 0.177 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 24 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.395 |
| p-value | 0.051 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
