General Structure Information
| PDB ID | 3dlx |
| HGNC Gene Label(s) | OXCT1 |
| Structure Name | crystal structure of human 3-oxoacid coa transferase 1 |
| Resolution | 2.2Å |
| Reference | AUTH K.L.KAVANAGH,N.SHAFQAT,W.W.YUE,S.PICAUD,J.W.MURRAY,AUTH 2 E.M.MACLEAN,F.VON DELFT,A.K.ROOS,C.H.ARROWSMITH,M.WIKSTROM,AUTH 3 A.M.EDWARDS,C.BOUNTRA,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN 3-OXOACID COA TRANSFERASE 1.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 470 |
| Number Of SNVs | 72 |
| Number Of Permutations | 38638 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.176 |
| p-value | 0.0 |
ClinVar
| Number Of Residues | 470 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2315 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.067 |
| p-value | 0.836 |
COSMIC
| Number Of Residues | 470 |
| Number Of SNVs | 6 |
| Number Of Permutations | 631 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.2 |
| p-value | 0.364 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 72 |
| Number Of ClinVar SNVs | 6 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.057 |
| p-value | 0.728 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 72 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | 0.53 |
| p-value | 0.045 |