General Structure Information
| PDB ID | 3bg0 |
| HGNC Gene Label(s) | SEC13 |
| Structure Name | architecture of a coat for the nuclear pore membrane |
| Resolution | 3.15Å |
| Reference | AUTH K.C.HSIA,P.STAVROPOULOS,G.BLOBEL,A.HOELZTITL ARCHITECTURE OF A COAT FOR THE NUCLEAR PORETITL 2 MEMBRANE.REF CELL(CAMBRIDGE,MASS.) V. 131 1313 2007REFN ISSN 0092-8674PMID 18160040DOI 10.1016/J.CELL.2007.11.038 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 281 |
| Number Of SNVs | 76 |
| Number Of Permutations | 26767 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.012 |
| p-value | 0.583 |
COSMIC
| Number Of Residues | 281 |
| Number Of SNVs | 3 |
| Number Of Permutations | 202 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.667 |
| p-value | 0.235 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.494 |
| p-value | 0.288 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
