General Structure Information
| PDB ID | 1pt6 |
| HGNC Gene Label(s) | ITGA1 |
| Structure Name | i domain from human integrin alpha1-beta1 |
| Resolution | 1.87Å |
| Reference | AUTH Y.NYMALM,J.S.PURANEN,T.K.M.NYHOLM,J.KAPYLA,H.KIDRON,AUTH 2 T.T.AIRENNE,J.HEINO,J.P.SLOTTE,M.S.JOHNSON,T.A.SALMINENTITL JARARHAGIN-DERIVED RKKH PEPTIDES INDUCE STRUCTURAL CHANGESTITL 2 IN ALPHA1I DOMAIN OF HUMAN INTEGRIN ALPHA1BETA1.REF J.BIOL.CHEM. V. 279 7962 2004REFN ISSN 0021-9258PMID 14660600DOI 10.1074/JBC.M312912200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 195 |
| Number Of SNVs | 46 |
| Number Of Permutations | 14653 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.06 |
| p-value | 0.538 |
COSMIC
| Number Of Residues | 195 |
| Number Of SNVs | 4 |
| Number Of Permutations | 291 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.667 |
| p-value | 0.054 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 46 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.471 |
| p-value | 0.097 |