General Structure Information
| PDB ID | 3q90 |
| HGNC Gene Label(s) | G3BP1 |
| Structure Name | crystal structure of the ntf2 domain of ras gtpase-activating protein- binding protein 1 |
| Resolution | 1.7Å |
| Reference | AUTH M.WELIN,L.TRESAUGUES,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,T.EKBLAD,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,I.JOHANSSON,T.KARLBERG,S.KOL,T.KOTENYOVA,AUTH 4 E.KOUZNETSOVA,M.MOCHE,T.NYMAN,C.PERSSON,H.SCHULER,P.SCHUTZ,AUTH 5 M.I.SIPONEN,A.G.THORSELL,S.VAN DER BERG,E.WAHLBERG,AUTH 6 J.WEIGELT,P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE NTF2 DOMAIN OF RASTITL 2 GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN 1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 129 |
| Number Of SNVs | 20 |
| Number Of Permutations | 2583 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.247 |
| p-value | 0.04 |
COSMIC
| Number Of Residues | 129 |
| Number Of SNVs | 3 |
| Number Of Permutations | 108 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.333 |
| p-value | 0.938 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 20 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.267 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
