General Structure Information
| PDB ID | 4bkx |
| HGNC Gene Label(s) | MTA1 |
| Structure Name | the structure of hdac1 in complex with the dimeric elm2-sant domain of mta1 from the nurd complex |
| Resolution | 3.0Å |
| Reference | AUTH C.J.MILLARD,P.J.WATSON,I.CELARDO,Y.GORDIYENKO,S.M.COWLEY,AUTH 2 C.V.ROBINSON,L.FAIRALL,J.W.R.SCHWABETITL CLASS I HDACS SHARE A COMMON MECHANISM OF REGULATION BYTITL 2 INOSITOL PHOSPHATES.REF MOL.CELL V. 51 57 2013REFN ISSN 1097-2765PMID 23791785DOI 10.1016/J.MOLCEL.2013.05.020 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 161 |
| Number Of SNVs | 19 |
| Number Of Permutations | 13519 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.023 |
| p-value | 0.114 |
COSMIC
| Number Of Residues | 161 |
| Number Of SNVs | 3 |
| Number Of Permutations | 7 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 0.67 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 19 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.585 |
| p-value | 0.223 |