General Structure Information
| PDB ID | 2xu7 |
| HGNC Gene Label(s) | RBBP4 |
| Structure Name | structural basis for rbap48 binding to fog-1 |
| Resolution | 1.9Å |
| Reference | AUTH S.LEJON,S.Y.THONG,A.MURTHY,S.ALQARNI,N.V.MURZINA,G.A.BLOBEL,AUTH 2 E.D.LAUE,J.P.MACKAYTITL INSIGHTS INTO ASSOCIATION OF THE NURD COMPLEX WITH FOG-1TITL 2 FROM THE CRYSTAL STRUCTURE OF AN RBAP48-FOG- 1 COMPLEX.REF J.BIOL.CHEM. V. 286 1196 2011REFN ISSN 0021-9258PMID 21047798DOI 10.1074/JBC.M110.195842 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 367 |
| Number Of SNVs | 16 |
| Number Of Permutations | 7094 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.125 |
| p-value | 0.102 |
COSMIC
| Number Of Residues | 367 |
| Number Of SNVs | 9 |
| Number Of Permutations | 4684 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.056 |
| p-value | 0.821 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 16 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | -0.125 |
| p-value | 0.808 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
