2NYL.B | PPP2R5C

General Structure Information

PDB ID 2nyl
HGNC Gene Label(s) PPP2R5C
Structure Name crystal structure of protein phosphatase 2a (pp2a) holoenzyme with the catalytic subunit carboxyl terminus truncated
Resolution 3.8Å
Reference AUTH Y.XU,Y.XING,Y.CHEN,Y.CHAO,Z.LIN,E.FAN,J.W.YU,S.STRACK,AUTH 2 P.D.JEFFREY,Y.SHITITL STRUCTURE OF THE PROTEIN PHOSPHATASE 2A HOLOENZYME.REF CELL(CAMBRIDGE,MASS.) V. 127 1239 2006REFN ISSN 0092-8674PMID 17174897DOI 10.1016/J.CELL.2006.11.033

Variant Set Distributions

ExAC Variants

Number Of Residues 377
Number Of SNVs 41
Number Of Permutations 19000
Optimal Distance Threshold 17.0
K Statistic 0.179
p-value 0.87
COSMIC

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants