General Structure Information
| PDB ID | 2qym |
| HGNC Gene Label(s) | PDE4C |
| Structure Name | crystal structure of unliganded pde4c2 |
| Resolution | 1.9Å |
| Reference | AUTH H.WANG,M.S.PENG,Y.CHEN,J.GENG,H.ROBINSON,AUTH 2 M.D.HOUSLAY,J.CAI,H.KETITL STRUCTURES OF THE FOUR SUBFAMILIES OFTITL 2 PHOSPHODIESTERASE-4 PROVIDE INSIGHT INTO THETITL 3 SELECTIVITY OF THEIR INHIBITORS.REF BIOCHEM.J. V. 408 193 2007REFN ISSN 0264-6021PMID 17727341DOI 10.1042/BJ20070970 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 291 |
| Number Of SNVs | 77 |
| Number Of Permutations | 10836 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.013 |
| p-value | 0.968 |
COSMIC
| Number Of Residues | 291 |
| Number Of SNVs | 7 |
| Number Of Permutations | 918 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.048 |
| p-value | 0.274 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 77 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.073 |
| p-value | 0.405 |