General Structure Information
| PDB ID | 1zmq |
| HGNC Gene Label(s) | DEFA6 |
| Structure Name | crystal structure of human alpha-defensin-6 |
| Resolution | 2.1Å |
| Reference | AUTH A.SZYK,Z.WU,K.TUCKER,D.YANG,W.LU,J.LUBKOWSKITITL CRYSTAL STRUCTURES OF HUMAN {ALPHA}-DEFENSINS HNP4, HD5, ANDTITL 2 HD6.REF PROTEIN SCI. V. 15 2749 2006REFN ISSN 0961-8368PMID 17088326DOI 10.1110/PS.062336606 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 32 |
| Number Of SNVs | 7 |
| Number Of Permutations | 121 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.333 |
| p-value | 0.413 |
COSMIC
| Number Of Residues | 32 |
| Number Of SNVs | 3 |
| Number Of Permutations | 25 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.667 |
| p-value | 0.202 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 7 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.333 |
| p-value | 0.35 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
