General Structure Information
| PDB ID | 2yuq |
| HGNC Gene Label(s) | ITK |
| Structure Name | solution structure of the sh3 domain of human tyrosine- protein kinase itk/tsk |
| Resolution | -1.0Å |
| Reference | AUTH H.ABE,K.MIYAMOTO,N.TOCHIO,M.SATO,S.KOSHIBA,AUTH 2 T.HARADA,S.WATANABE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF HUMANTITL 2 TYROSINE-PROTEIN KINASE ITK/TSKREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 78 |
| Number Of SNVs | 15 |
| Number Of Permutations | 1571 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.133 |
| p-value | 0.508 |
COSMIC
| Number Of Residues | 78 |
| Number Of SNVs | 3 |
| Number Of Permutations | 217 |
| Optimal Distance Threshold | 36.0 |
| K Statistic | 0.667 |
| p-value | 0.393 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
