General Structure Information
| PDB ID | 3jui |
| HGNC Gene Label(s) | EIF2B5 |
| Structure Name | crystal structure of the c-terminal domain of human translation initiation factor eif2b epsilon subunit |
| Resolution | 2.0Å |
| Reference | AUTH J.WEI,H.XU,C.ZHANG,M.WANG,F.GAO,W.GONGTITL CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMANTITL 2 TRANSLATION INITIATION FACTOR EIF2B EPSILON SUBUNITREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 162 |
| Number Of SNVs | 28 |
| Number Of Permutations | 2261 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.114 |
| p-value | 0.266 |
COSMIC
| Number Of Residues | 162 |
| Number Of SNVs | 4 |
| Number Of Permutations | 218 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.167 |
| p-value | 0.552 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 28 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.135 |
| p-value | 0.558 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
