3H3G.A | PTH1R

General Structure Information

PDB ID 3h3g
HGNC Gene Label(s) PTH1R
Structure Name crystal structure of the extracellular domain of the human parathyroid hormone receptor (pth1r) in complex with parathyroid hormone-related protein (pthrp)
Resolution 1.94Å
Reference AUTH A.A.PIOSZAK,N.R.PARKER,T.J.GARDELLA,H.E.XUTITL STRUCTURAL BASIS FOR PARATHYROID HORMONE-RELATED PROTEINTITL 2 BINDING TO THE PARATHYROID HORMONE RECEPTOR AND DESIGN OFTITL 3 CONFORMATION-SELECTIVE PEPTIDES.REF J.BIOL.CHEM. V. 284 28382 2009REFN ISSN 0021-9258PMID 19674967DOI 10.1074/JBC.M109.022905

Variant Set Distributions

ExAC Variants

Number Of Residues 100
Number Of SNVs 29
Number Of Permutations 15113
Optimal Distance Threshold 15.0
K Statistic 0.268
p-value 0.14

Mapped Variants

[+] ExAC Missense Variants