General Structure Information
| PDB ID | 2leb |
| HGNC Gene Label(s) | SRSF2 |
| Structure Name | solution structure of human srsf2 (sc35) rrm in complex with 5- uccagu-3 |
| Resolution | -1.0Å |
| Reference | AUTH G.M.DAUBNER,A.CLERY,S.JAYNE,J.STEVENIN,F.H.ALLAINTITL A SYN-ANTI CONFORMATIONAL DIFFERENCE ALLOWS SRSF2 TOTITL 2 RECOGNIZE GUANINES AND CYTOSINES EQUALLY WELL.REF EMBO J. V. 31 162 2012REFN ISSN 0261-4189PMID 22002536DOI 10.1038/EMBOJ.2011.367 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 101 |
| Number Of SNVs | 5 |
| Number Of Permutations | 239 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.2 |
| p-value | 0.365 |
COSMIC

Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC

Pathogenic Proximity Analysis
COSMIC PathProx Analysis

