General Structure Information
| PDB ID | 4ckr |
| HGNC Gene Label(s) | DDR1 |
| Structure Name | crystal structure of the human ddr1 kinase domain in complex with ddr1-in-1 |
| Resolution | 2.2Å |
| Reference | AUTH H.KIM,L.TAN,E.L.WEISBERG,F.LIU,P.CANNING,H.G.CHOI,S.A.EZELL,AUTH 2 H.WU,Z.ZHAO,J.WANG,A.MANDINOVA,J.D.GRIFFIN,A.N.BULLOCK,AUTH 3 Q.LIU,S.W.LEE,N.S.GRAYTITL DISCOVERY OF A POTENT AND SELECTIVE DDR1 RECEPTOR TYROSINETITL 2 KINASE INHIBITOR.REF ACS CHEM.BIOL. V. 8 2145 2013REFN ISSN 1554-8929PMID 23899692DOI 10.1021/CB400430T |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 294 |
| Number Of SNVs | 66 |
| Number Of Permutations | 12088 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.163 |
| p-value | 0.075 |