General Structure Information
| PDB ID | 1y8x |
| HGNC Gene Label(s) | UBE2M |
| Structure Name | structural basis for recruitment of ubc12 by an e2-binding domain in nedd8s e1 |
| Resolution | 2.4Å |
| Reference | AUTH D.T.HUANG,A.PAYDAR,M.ZHUANG,M.B.WADDELL,J.M.HOLTON,AUTH 2 B.A.SCHULMANTITL STRUCTURAL BASIS FOR RECRUITMENT OF UBC12 BY AN E2TITL 2 BINDING DOMAIN IN NEDD8S E1.REF MOL.CELL V. 17 341 2005REFN ISSN 1097-2765PMID 15694336DOI 10.1016/J.MOLCEL.2004.12.020 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 155 |
| Number Of SNVs | 14 |
| Number Of Permutations | 1645 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.044 |
| p-value | 0.784 |
COSMIC
| Number Of Residues | 155 |
| Number Of SNVs | 3 |
| Number Of Permutations | 248 |
| Optimal Distance Threshold | 41.0 |
| K Statistic | 0.667 |
| p-value | 0.375 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 14 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.484 |
| p-value | 0.106 |