General Structure Information
| PDB ID | 3u9c |
| HGNC Gene Label(s) | CSNK2A1 |
| Structure Name | structure of a c-terminal deletion mutant of human protein kinase ck2 catalytic subunit with the atp-competitive inhibitor resorufin |
| Resolution | 3.2Å |
| Reference | AUTH K.KLOPFFLEISCH,O.G.ISSINGER,K.NIEFINDTITL LOW-DENSITY CRYSTAL PACKING OF HUMAN PROTEIN KINASE CK2TITL 2 CATALYTIC SUBUNIT IN COMPLEX WITH RESORUFIN OR OTHERTITL 3 LIGANDS: A TOOL TO STUDY THE UNIQUE HINGE-REGION PLASTICITYTITL 4 OF THE ENZYME WITHOUT PACKING BIAS.REF ACTA CRYSTALLOGR.,SECT.D V. 68 883 2012REFN ISSN 0907-4449PMID 22868753DOI 10.1107/S0907444912016587 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 331 |
| Number Of SNVs | 16 |
| Number Of Permutations | 8757 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.0 |
| p-value | 0.751 |
COSMIC
| Number Of Residues | 331 |
| Number Of SNVs | 7 |
| Number Of Permutations | 3485 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.286 |
| p-value | 0.388 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 16 |
| Number Of COSMIC SNVs | 8 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.095 |
| p-value | 0.975 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
