General Structure Information
| PDB ID | 2m0p |
| HGNC Gene Label(s) | LRP2 |
| Structure Name | solution structure of the tenth complement type repeat of human megalin |
| Resolution | -1.0Å |
| Reference | AUTH R.DAGIL,C.OSHEA,A.NYKJAR,A.M.BONVIN,B.B.KRAGELUNDTITL GENTAMICIN BINDS TO THE MEGALIN RECEPTOR AS A COMPETITIVETITL 2 INHIBITOR USING THE COMMON LIGAND BINDING MOTIF OFTITL 3 COMPLEMENT TYPE REPEATS: INSIGHT FROM THE NMR STRUCTURE OFTITL 4 THE 10TH COMPLEMENT TYPE REPEAT DOMAIN ALONE AND IN COMPLEXTITL 5 WITH GENTAMICIN.REF J.BIOL.CHEM. V. 288 4424 2013REFN ISSN 0021-9258PMID 23275343DOI 10.1074/JBC.M112.434159 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 46 |
| Number Of SNVs | 7 |
| Number Of Permutations | 801 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.333 |
| p-value | 0.637 |