General Structure Information
| PDB ID | 4my2 |
| HGNC Gene Label(s) | NDP |
| Structure Name | crystal structure of norrin in fusion with maltose binding protein |
| Resolution | 2.4Å |
| Reference | AUTH J.KE,K.G.HARIKUMAR,C.ERICE,C.CHEN,X.GU,L.WANG,N.PARKER,AUTH 2 Z.CHENG,W.XU,B.O.WILLIAMS,K.MELCHER,L.J.MILLER,H.E.XUTITL STRUCTURE AND FUNCTION OF NORRIN IN ASSEMBLY AND ACTIVATIONTITL 2 OF A FRIZZLED 4-LRP5/6 COMPLEX.REF GENES DEV. V. 27 2305 2013REFN ISSN 0890-9369PMID 24186977DOI 10.1101/GAD.228544.113 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 104 |
| Number Of SNVs | 10 |
| Number Of Permutations | 1980 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.222 |
| p-value | 0.415 |
ClinVar
| Number Of Residues | 104 |
| Number Of SNVs | 15 |
| Number Of Permutations | 2861 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.457 |
| p-value | 0.114 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 10 |
| Number Of ClinVar SNVs | 15 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.2 |
| p-value | 0.282 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
