2CR4.A | SH3BP2

PDB ID	2cr4
HGNC Gene Label(s)	SH3BP2
Structure Name	solution structure of the sh2 domain of human sh3bp2 protein
Resolution	-1.0Å
Reference	AUTH R.HATTA,T.TOMIZAWA,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH2 DOMAIN OF HUMANTITL 2 SH3BP2 PROTEINREF TO BE PUBLISHEDREFN

ExAC Variants

Position	Variant	AA Change	PDB Chain Position	Structure Coordinates
4:2833657		L>R	A:15	(-2.60, 2.01, -10.32)
4:2833665	rs145949614	S>P	A:18	(-8.91, -2.25, -6.66)
4:2833666	rs199818232	S>L	A:18	(-8.91, -2.25, -6.66)
4:2833674	COSM3696612	V>I	A:21	(-8.14, -0.00, 0.94)
4:2833681		T>I	A:23	(-8.27, -0.08, 5.08)
4:2833684	rs201536400	T>M	A:24	(-6.51, 3.55, 7.85)
4:2833704		R>G	A:31	(-9.85, -10.69, 8.17)
4:2834066		K>R	A:34	(-4.94, -14.28, 4.12)
4:2834072		T>I	A:36	(-9.86, -11.25, -2.00)
4:2834081		R>Q	A:39	(-7.62, -22.53, -3.45)
4:2834086		E>K	A:41	(-4.45, -19.06, -0.20)
4:2834089		P>A	A:42	(-2.81, -14.49, -0.11)
4:2834099		G>A	A:45	(3.12, -10.41, -4.64)
4:2834113	rs373554386	R>W	A:50	(-2.52, 1.03, 4.32)
4:2834114		R>Q	A:50	(-2.52, 1.03, 4.32)
4:2834132	rs377411211	S>L	A:56	(-4.34, 12.83, 2.36)
4:2834724		V>G	A:61	(0.72, -2.82, 2.08)
4:2834735	COSM173268	E>K	A:65	(3.73, -15.86, -0.46)
4:2834760		Y>C	A:73	(7.06, -0.84, 1.05)
4:2834762	rs369562627	R>C	A:74	(5.51, 7.48, 4.56)
4:2834763	rs373119331	R>H	A:74	(5.51, 7.48, 4.56)
4:2835448	rs142735744	E>K	A:87	(16.76, 9.90, -5.31)
4:2835452		V>A	A:88	(14.16, 6.90, -6.76)
4:2835460		V>L	A:91	(5.01, 11.25, -12.87)
4:2835464		S>I	A:92	(2.55, 8.52, -11.80)
4:2835467		V>A	A:93	(1.42, 4.91, -8.44)
4:2835482	rs547977985	E>G	A:98	(5.85, -0.12, -14.71)
4:2835499	rs201983777	V>M	A:104	(13.66, -5.97, -5.46)
4:2835530	rs374608155	R>Q	A:114	(3.96, -12.25, -8.42)
4:2835534		H>Q	A:115	(-0.19, -10.81, -9.42)
4:2835541	rs201197278	G>S	A:118	(-8.52, -7.09, -5.42)

2CR4.A | SH3BP2.