General Structure Information
| PDB ID | 4iyp |
| HGNC Gene Label(s) | IGBP1 |
| Structure Name | structure of the npp2ac-alpha4 complex |
| Resolution | 2.8Å |
| Reference | AUTH L.JIANG,V.STANEVICH,K.A.SATYSHUR,M.KONG,G.R.WATKINS,AUTH 2 B.E.WADZINSKI,R.SENGUPTA,Y.XINGTITL STRUCTURAL BASIS OF PROTEIN PHOSPHATASE 2A STABLE LATENCY.REF NAT COMMUN V. 4 1699 2013REFN ESSN 2041-1723PMID 23591866DOI 10.1038/NCOMMS2663 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 199 |
| Number Of SNVs | 23 |
| Number Of Permutations | 4507 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.253 |
| p-value | 0.26 |
COSMIC
| Number Of Residues | 199 |
| Number Of SNVs | 4 |
| Number Of Permutations | 93 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.167 |
| p-value | 0.998 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 23 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | -0.134 |
| p-value | 0.932 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
