General Structure Information
| PDB ID | 4iul |
| HGNC Gene Label(s) | EIF4G2 |
| Structure Name | mif4g domain of dap5 |
| Resolution | 2.3Å |
| Reference | AUTH G.VIRGILI,F.FRANK,K.FEOKTISTOVA,M.SAWICKI,N.SONENBERG,AUTH 2 C.S.FRASER,B.NAGARTITL STRUCTURAL ANALYSIS OF THE DAP5 MIF4G DOMAIN AND ITSTITL 2 INTERACTION WITH EIF4A.REF STRUCTURE V. 21 517 2013REFN ISSN 0969-2126PMID 23478064DOI 10.1016/J.STR.2013.01.015 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 234 |
| Number Of SNVs | 23 |
| Number Of Permutations | 11211 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.241 |
| p-value | 0.634 |
COSMIC
| Number Of Residues | 234 |
| Number Of SNVs | 4 |
| Number Of Permutations | 541 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.119 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 23 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.25 |
| p-value | 0.209 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
