General Structure Information
| PDB ID | 2fdb |
| HGNC Gene Label(s) | FGF8 |
| Structure Name | crystal structure of fibroblast growth factor (fgf)8b in complex with fgf receptor (fgfr) 2c |
| Resolution | 2.28Å |
| Reference | AUTH S.K.OLSEN,J.Y.H.LI,C.BROMLEIGH,A.V.ELISEENKOVA,AUTH 2 O.A.IBRAHIMI,Z.LAO,F.ZHANG,R.J.LINHARDT,A.L.JOYNER,AUTH 3 M.MOHAMMADITITL STRUCTURAL BASIS BY WHICH ALTERNATIVE SPLICINGTITL 2 MODULATES THE ORGANIZER ACTIVITY OF FGF8 IN THETITL 3 BRAINREF GENES DEV. V. 20 185 2006REFN ISSN 0890-9369PMID 16384934DOI 10.1101/GAD.1365406 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 147 |
| Number Of SNVs | 31 |
| Number Of Permutations | 2814 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.297 |
| p-value | 0.595 |
ClinVar
| Number Of Residues | 147 |
| Number Of SNVs | 3 |
| Number Of Permutations | 106 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.333 |
| p-value | 0.131 |
Ripley’s K Analysis Plots
ExACClinVar
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 31 |
| Number Of ClinVar SNVs | 3 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.299 |
| p-value | 0.174 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
