General Structure Information
| PDB ID | 3v3k |
| HGNC Gene Label(s) | CASP9 |
| Structure Name | human caspase 9 in complex with bacterial effector protein |
| Resolution | 3.49Å |
| Reference | AUTH M.MOERTL,K.MASKOS,H.STEUBERTITL HUMAN CASPASE 9 IN COMPLEX WITH BACTERIAL EFFECTOR PROTEINREF PLOS ONE 2013REFN ESSN 1932-6203 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 233 |
| Number Of SNVs | 63 |
| Number Of Permutations | 10165 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.025 |
| p-value | 0.809 |
COSMIC
| Number Of Residues | 233 |
| Number Of SNVs | 3 |
| Number Of Permutations | 170 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.667 |
| p-value | 0.789 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 63 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | -0.286 |
| p-value | 0.998 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
