1HUR.A | ARF1

General Structure Information

PDB ID 1hur
HGNC Gene Label(s) ARF1
Structure Name human adp-ribosylation factor 1 complexed with gdp, full length non-myristoylated
Resolution 2.0Å
Reference AUTH J.C.AMOR,D.H.HARRISON,R.A.KAHN,D.RINGETITL STRUCTURE OF THE HUMAN ADP-RIBOSYLATION FACTOR 1TITL 2 COMPLEXED WITH GDP.REF NATURE V. 372 704 1994REFN ISSN 0028-0836PMID 7990966DOI 10.1038/372704A0

Variant Set Distributions

ExAC Variants

Number Of Residues 180
Number Of SNVs 8
Number Of Permutations 609
Optimal Distance Threshold 6.0
K Statistic 0.143
p-value 0.042
COSMIC

Number Of Residues 180
Number Of SNVs 3
Number Of Permutations 67
Optimal Distance Threshold 20.0
K Statistic 0.333
p-value 1.0

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 8
Number Of COSMIC SNVs 3
Optimal Distance Threshold 16.0
K Statistic -0.536
p-value 0.048

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants