General Structure Information
| PDB ID | 3w98 |
| HGNC Gene Label(s) | HIST1H3H |
| Structure Name | crystal structure of human nucleosome core particle lacking h3.1 n- terminal region |
| Resolution | 3.42Å |
| Reference | AUTH W.IWASAKI,Y.MIYA,N.HORIKOSHI,A.OSAKABE,H.TAGUCHI,AUTH 2 H.TACHIWANA,T.SHIBATA,W.KAGAWA,H.KURUMIZAKATITL CONTRIBUTION OF HISTONE N-TERMINAL TAILS TO THE STRUCTURETITL 2 AND STABILITY OF NUCLEOSOMESREF FEBS OPEN BIO V. 3 363 2013REFN ESSN 2211-5463PMID 24251097DOI 10.1016/J.FOB.2013.08.007 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 99 |
| Number Of SNVs | 45 |
| Number Of Permutations | 22919 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.344 |
| p-value | 0.697 |
COSMIC
| Number Of Residues | 99 |
| Number Of SNVs | 6 |
| Number Of Permutations | 744 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.2 |
| p-value | 0.909 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 45 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.207 |
| p-value | 0.718 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
