General Structure Information
| PDB ID | 1z29 |
| HGNC Gene Label(s) | SULT1A2 |
| Structure Name | crystal structures of sult1a2 and sult1a1*3: implications in the bioactivation of n-hydroxy-2-acetylamino fluorine (oh-aaf) |
| Resolution | 2.4Å |
| Reference | AUTH J.LU,H.LI,J.ZHANG,M.LI,M.Y.LIU,X.AN,M.C.LIU,W.CHANGTITL CRYSTAL STRUCTURES OF SULT1A2 AND SULT1A1 *3: INSIGHTS INTOTITL 2 THE SUBSTRATE INHIBITION AND THE ROLE OF TYR149 IN SULT1A2.REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 396 429 2010REFN ISSN 0006-291XPMID 20417180DOI 10.1016/J.BBRC.2010.04.109 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 281 |
| Number Of SNVs | 77 |
| Number Of Permutations | 23049 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.099 |
| p-value | 0.029 |
COSMIC
| Number Of Residues | 281 |
| Number Of SNVs | 4 |
| Number Of Permutations | 16 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 77 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.319 |
| p-value | 0.234 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
