General Structure Information
| PDB ID | 1rm8 |
| HGNC Gene Label(s) | MMP16 |
| Structure Name | crystal structure of the catalytic domain of mmp-16/mt3- mmp: characterization of mt-mmp specific features |
| Resolution | 1.8Å |
| Reference | AUTH R.LANG,M.BRAUN,N.E.SOUNNI,A.NOEL,F.FRANKENNE,AUTH 2 J.M.FOIDART,W.BODE,K.MASKOSTITL CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OFTITL 2 MMP-16/MT3-MMP: CHARACTERIZATION OF MT-MMPTITL 3 SPECIFIC FEATURES.REF J.MOL.BIOL. V. 336 213 2004REFN ISSN 0022-2836PMID 14741217DOI 10.1016/J.JMB.2003.12.022 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 169 |
| Number Of SNVs | 16 |
| Number Of Permutations | 5592 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.067 |
| p-value | 0.735 |
COSMIC
| Number Of Residues | 169 |
| Number Of SNVs | 5 |
| Number Of Permutations | 699 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.2 |
| p-value | 0.601 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 16 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.65 |
| p-value | 0.25 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
